Guidelines for Admission in Common Fevers and Infectious Diseases

     

Any of the following criteria are to be met for admission in a hospital and in-hospital treatment:

Febrile Illness Clinical key pointers for Admission:

  • Fever >= 38.3'C or >=101'F for more than 2 days
  • Any Fever for more than 5 days – not responding to OP treatments – worsening symptoms
  • Along with any or all of following: Headache, Dizziness, Pain in Muscles and Joints, Weakness
  • Patients presenting with AFI and signs of organ dysfunction and symptoms/signs suggestive of sepsis, like
    • Grossly deranged Liver function tests, Renal Function tests,
    • Patches in lungs / ARDS
    • Deranged CNS – having: drowsiness of altered sensorium / hypotension or cardiac suppression / repeated vomiting or loose stools with signs of dehydration / not able take orally with signs of dehydration / oliguria)
  • Other signs such as those mentioned below can also justify admission
    • Severe Hypotension -
    • Toxic look
    • Febrile Seizures
    • Petechial or purpuric rash
  • Elderly patients more than 65 years of age with comorbid conditions
  • Respiration: respiratory rate more than 22/min; cyanosis; arterial oxygen saturation less than 92% on room air
  • Circulation – blood pressure – systolic less than 100mm Hg; capillary refill > 3 secs
  • Very high WBC count(>12,000/cmm) – indicating septicaemia or sepsis
  • Hemophagocytic Lymphohistiocytosis (HLH)

Ref:

  • IMA guidelines
  • Bhargava A, Ralph R, Chatterjee B, et al. Assessment and initial management of acute undifferentiated fever in tropical and subtropical regions. BMJ. 2018;363: k4766. Published 2018 Nov 29. DOI:10.1136/bmj. k4766

*Antibiotic use – As per the approved antibiotic policy of the hospital

Admission Criteria for Fever in Children

  • Seizures, difficulty to stay awake, and stiff neck
  • Toxic appearance, listlessness
  • Lethargy 
  • Irritability 
  • Dehydration 
  • Severe malnutrition 
  • Toxic appearance 
  • Inability to feed 
  • A 14-day illness without a confirmed diagnosis 

Other Red Flags:

Additional signs that warrant immediate attention and potential hospital admission include:

  • Bleeding: red spots or patches on the skin, bleeding from nose or gums, vomiting blood, black stools, heavy menstruation/vaginal bleeding  - Petechiae or purpura
  • Frequent vomiting 
  • Severe abdominal pain 
  • Drowsiness, mental confusion, or seizures 
  • Pale, cold, or clammy hands and feet 
  • Difficulty breathing - Respiratory distress
  • Signs of dehydration 
  • Lethargy or unconsciousness 
  • Sunken eyes 
  • Slow skin pinch recoil 
  • Red maculopapular rash: May be associated with conditions like measles, rubella, or dengue 
  • Fine generalized maculopapular rash with systemic dysfunction/shock: Could be indicative of meningococcemia 

Ref –

  • IMA guidelines
  • Schellack N, Schellack, G. An overview of the management of fever and its possible complications in infants and toddlers. SA Pharm J. 2018. 85. 26–33

 Admission Criteria for Dengue fever:

  • ADMISSION CRITERIA
    • Persistent vomiting
    • Dehydration
    • Abdominal tenderness
    • Hepatomegaly
    • Ascites
    • Oedema
    • Mucosal bleed
    • blood in vomit or stool
    • pale and cold skin
  • Respiratory distress
  • Pleural effusion
  • Hypotension/shock - drop in Systolic BP of ≥20mmHg and diastolic of ≥10 mmHg indicates postural hypotension
  • Oliguria
  • Rising Haematocrit> 60%
  • Drastic rapid decrease in platelets or any platelet count with bleeding symptoms
  • Ascites/ pleural effusion / hypotension / polyserositis / dengue haemorrhagic fevers / dengue shock
  • Dengue haemorrhagic fever – thrombocytopenia – mucosal and gastrointestinal bleeds – rise in haematocrit
  • Dengue shock syndrome – weak pulse – hypotension
  • Expanded dengue syndrome – encephalitis – myocarditis – hepatitis – renal failure – ARDS – haemophagocytosis
  • Dengue Haemorrhagic Fever (DHF) with the following criteria:

 

Grade

Symptoms/signs

Laboratory finding

DHF

I

Headache , Retro-orbital pain , Myalgia , Arthralgia + positive TOURNIQUET TEST or signs of plasma leakage

Thrombocytopenia : Platelet count less than 100,000/cu.mm.  Haematocrit rise 20% or more

DHF

II

Above signs + evidence of spontaneous bleeding in skin or other organs ( black tarry stools, epistaxis , bleeding from gums etc) and abdominal pain

Thrombocytopenia : Platelet count less than 100,000/cu.mm.  Haematocrit rise 20% or more

DHF

III

Above signs + circulating failure (weak rapid pulse, pulse pressure less than 20mmHg or high Diastolic pressure, hypotension with presence of cold clammy skin and restlessness)

Thrombocytopenia : Platelet count less than 100,000/cu.mm.  Haematocrit rise 20% or more

DHF

IV

Profound shock with undetectable blood pressure or pulse

Thrombocytopenia : Platelet count less than 100,000/cu.mm.  Haematocrit rise 20% or more

 

  • Metabolic acidosis/ hyperpnoea/ Kussmaul’s breathing
  • Oliguria or anuria
  • Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≥1000 units/L
  • Impaired consciousness (GCS < 9)
  • Febrile seizures in young children •
  • Nervous System - Encephalopathy - Encephalitis/aseptic meningitis • Intracranial haemorrhages/thrombosis • Subdural effusions • Mononeuropathies/polyneuropathies/Guillane-Barre Syndrome • Transverse myelitis
  • Gastrointestinal system : Hepatitis/fulminant hepatic failure • Acalculous cholecystitis • Acute pancreatitis • Hyperplasia of Peyer’s patches • Acute parotitis
  • Kidney : Acute renal failure • Hemolytic uremic syndrome(HUS)
  • Heart -Conduction abnormalities • Myocarditis • Pericarditis
  • Lungs - Acute respiratory distress syndrome • Pulmonary haemorrhage
  • Musculoskeletal system - Myositis with raised creatine phosphokinase (CPK) • Rhabdomyolysis Lymphoreticular system •
  • Infection associated haemophagocytic syndrome - Haemophagocytic lymphohistiocytosis (HLH) • Idiopathic thrombocytopenic purura (ITP) • Spontaneous splenic rupture • Lymph node infarction
  • Eye - Macular haemorrhage • Impaired visual acuity • Optic neuritis

 

  • INDICATIONS FOR PLATELET TRANSFUSION
    • For adults: platelets < 40000 and with bleeding symptoms
    • Platelet count less than 10000.
    • Prolonged shock with coagulopathy ]
    • Systemic massive bleeding

Ref:

  • IMA guidelines
  • National Vector Control Board Guidelines( followed by AIIMS)/ Ministry of Family Health & Welfare - Guidelines – 2008 and 2023
  • WHO guidelines
  • The Indian Society of Critical Care Medicine Tropical Fever Group, Singhi S, Chaudhary D, et al. Tropical fevers: Management guidelines. Indian J Crit Care Med. 2014;18(2):62-69. DOI:10.4103/0972–5229.126074
  • Guidelines for management of co-infection of COVID-19 with other seasonal epidemic prone diseases. Available at: https://www. mohfw.gov.in/pdf/GuidelinesformanagementofcoinfectionofCOVID19withotherseasonalepidemicpronediseases.pdf. Accessed on: 03 September 2021
  • National Health Mission. Guidelines for management of dengue fever. Available at: https://www.nhm.gov.in/images/pdf/ guidelines/nrhm-guidelines/stg/dengue.pdf. Accessed on: 03 September 2021

Admission Criteria for Pneumonia in Children

  • Important Signs
    • Cough , cold with or without Fever, that includes fast breathing and chest indrawing
    • Along with inability to drink or persistent vomiting or convulsions or lethargy/unconscious, Stridor or severe Malnutrition
    • Admission justified in severe pneumonia as per ICMR protocols

Ref:

https://www.icmr.gov.in/icmrobject/uploads/STWs/1725952336_paediatrics_severe_pneumonia.pdf

Admission Criteria for Pneumonia in Adult

  • Breathlessness, Pleuritic Chest pain, Malaise, arthralgia, Hemoptysis
  • Criticality parameters – Respiratory Rate - >30/min, Abdominothoracic respiration, Cyanosis, Inability to speak long sentences
  • ARDS
  • Breathlessness at rest or on exertion
  • Oxygen saturation less than 92%
  • With COPD or Interstitial lung disease or any restrictive lung disease
  • Admission – Score 1 to 4 are advised admission as per ICMR protocols

Ref:

https://www.icmr.gov.in/icmrobject/uploads/STWs/1725963734_pulmonology_acute_respiratory_infections.pdf

Admission Criteria in Diarrhea/Acute  Gastroenteritis

  • >3 loose or watery stools per day or blood in stool (Dysentery)
  • And any 2 of the following signs
    • Lethargy/Unconscious
    • Sunken eyes
    • Not able to Drink/Drinking poorly
    • Skin pinch – goes back slowly

Admission Criteria for Hepatitis / other Jaundice

  • INR >1.5 or rising INR
  • Altered sensorium
  • Bleeding
  • Recurrent vomiting with dehydration
  • Hypotension (Systolic BP<90 mmHg)

Ref:

https://www.icmr.gov.in/icmrobject/uploads/STWs/1725952338_paediatrics_diarrhea.pdf

Admission criteria for Acute Rhinosinusitis /URI

  • Known Diabetic /Immunocompromised
  • Suspicion of Complications like
    • Orbital involvement (Periorbital edema/Erythema, Displaced globe, Ophthalmoplegia, Visual Disturbances)
    • Meningitis/ Altered Sensorium
    • Frontal Fullness
  • Non Resolution with Oral antibiotics for 7 days
  • Pointers for invasive Fungal sinusitis (Facial Hypoesthesia, facial skin,/palatal/turbinate discoloration)

Ref:

Refer Pg8(https://www.icmr.gov.in/icmrobject/uploads/STWs/1725952349_ent.pdf )

https://www.icmr.gov.in/icmrobject/uploads/STWs/1725952349_ent_pharyngitis_and_sore_throat.pdf

  • The participating hospitals are requested to take herewith the above guidelines for admission and basic treatment as a guidepost to decide upon admission and basic treatment for the commonly encountered fevers and infections as mentioned above – in exceptional cases the protocol may be decided by the treating Doctor as the case may be and depending on the clinical scenario and clinical features of the patient.
  • Request that any deviation from the above published guidelines should be justified clinically and supported with any suitable nationally or internationally accepted published guidelines.